Isaac married Barbara Royer in Oct 1862. Barbara (daughter of Amos Royer and Elizabeth Frasher) was born on 30 Jan 1835 in Pennsylvania; died on 8 Apr 1899; was buried in Pine Hall Cemetery, State College, Centre County PA. [Group Sheet] [Family Chart]

1. Elizabeth Mariah Reish was born on 2 Jan 1865 in Centre County, PA; died on 11 Apr 1922 in Ferguson Township, Centre County, PA; was buried in Pine Hall Cemetery, State College, Centre County PA.
2. Hannah Jane Reish was born on 19 Jul 1863 in Centre County, PA; died on 5 Mar 1924 in Spring Township, Centre County, PA; was buried on 8 Mar 1924 in Lutheran Church Cemetery, Pleasant Gap, Centre County, PA.